Method of Evaluation of the Bitterness of Clarithromycin Dry Syrup.
نویسندگان
چکیده
منابع مشابه
Method of evaluation of the bitterness of clarithromycin dry syrup.
The degree of bitterness of clarithromycin (CAM) dry syrup was evaluated using several methods. Using the inversion method, shaking method, and paddle method, a reasonable correlation between the bitter taste and the amount dissolved was not observed. A mini-column with inner diameter of 0.76 cm and height of 5 cm packed with CAM dry syrup was used for the release test. The release rate of CAM ...
متن کاملQuality of twelve clarithromycin dry syrup formulations-bitterness, grittiness and uniformity of drug loading.
The objective of the study was to evaluate the bitterness, grittiness and uniformity of drug loading as measures of the quality of 12 formulations of clarithromycin dry syrup (CAMDS), comprising one branded and 11 generic products. Some of the generic CAMDS formulations were more bitter than the branded product while others had similar bitterness when tested as aqueous suspensions. Only one gen...
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ژورنال
عنوان ژورنال: Chemical and Pharmaceutical Bulletin
سال: 2002
ISSN: 0009-2363,1347-5223
DOI: 10.1248/cpb.50.147